THE ROLE OF AVOCADO OIL AS ANTI-DYSLIPIDEMIA AND HEPATOPROTECTIV
Keywords:
avocado oil, dyslipidemia, , hepatoprotectiveAbstract
Avocado oil contains Monounsaturated Fatty Acid and Polyunsaturated Fatty Acid with the main fatty acid being oleic acid at 59.46-67.69% and containing beta sitosterol as a phytosterol The main thing contained in avocado oil. The content of avocado oil has many benefits for the body, such as being able to reduce lipid profile levels, there by preventing and protecting the body from heart disease and as a hepatoprotective agent. Identify and summarize various literature studies by answering questions specifically related to the benefits of avocado oil on dyslipidemia and the liver?. Literature search using 3 bibliographic database searches (science direct, Pubmed, and Demensions) published in the last 10 years (2013-2023). Using the Preferred Reporting Items for Systematic Review Extension for Scoping Review (PRISMA-ScR) guide. Descriptive findings The initial search was 3266 articles from database searches. The final results were found, namely 10 articles which significantly showed that the content in avocado oil was able to act as anti-dyslipidemia and hepatoprotective. Avocado oil avocado oil is significantly able to overcome dyslipidemia and to protect the liver.
References
I. D. N. Supariasa and D. Handayani, Asuhan Gizi Klinik, 1st ed. Jakarta: EGC, 2019.
N. T. Yustiani, Mutmainnah, and M. Arif, “Hubungan Derajat Perlemakan Hati Non-Alkoholik Dengan Aktivitas Aminotransferase Serum,” Indones. J. Clin. Pathol. Med. Lab., vol. 16, no. 1, p. 26, 2018, doi: 10.24293/ijcpml.v16i1.1027.
BPS, “Produksi Tanaman Buah-buahan Tahunan,” https://www.bps.go.id/indicator/55/62/3/produksi-tanaman-buah-buahan.html. 2021.
N. A. Putri and M. Sri Gumilar, “Efek Hipolidemik Alpukat (Persea americana) Pada Hiperkolesterolmia: Literatur Review,” J. Bahana Kesehat. Masy. (Bahana J. Public Heal., vol. 3, no. 2, pp. 108–114, 2019, doi: 10.35910/jbkm.v3i2.230.
M. Flores, C. Saravia, C. Vergara, F. Avila, H. V.- Molecules, and undefined 2019, “Avocado oil: Characteristics, properties, and applications,” mdpi.com.
C. T.-J. of functional foods and undefined 2019, “Virgin avocado oil: An emerging source of functional fruit oil,” Elsevier.
A. C. Brown, Understanding Food Principles and Preparation, 6th ed. Amerika Serikat: Cengage Learning, 2018.
A. P. Rahardjo, Y. Manaf, M. Ambarita, and B. Nusantoro, Minyak Goreng Untuk Pengolahan Pangan, 1st ed. yogyakarta: Gadjah Mada University Press, 2021.
M. N. H. Putri, M. A. Dewi, and D. Handayani, “Efek Diet Ketogenik Pada Diabetes Mellitus Tipe 2: Scoping Review,” Amerta Nutr., vol. 6, no. 3, pp. 326–341, 2022, doi: 10.20473/amnt.v6i3.2022.326-341.
M. Shahbandeh, “Consumption of vegetable oils worldwide from 2013/14 to 2022/2023, by oil type(in million metric tons),” statista, 2023. https://www.statista.com/statistics/263937/vegetable-oils-global-consumption/#:~:text=This statistic shows the global,metric tons in 2021%2F22. (accessed Aug. 01, 2023).
B. Bojková, P. J. Winklewski, and M. Wszedybyl-Winklewska, “Dietary fat and cancer—which is good, which is bad, and the body of evidence,” Int. J. Mol. Sci., vol. 21, no. 11, pp. 1–56, 2020, doi: 10.3390/ijms21114114.
Y. Li, X. Li, Q. Xue, J. Wang, and J. Tan, “High-fat diet and dyslipidemia synergistically contribute to T cell senescence in gut associated lymphoid tissue,” Exp. Gerontol., vol. 151, no. 157, 2021, doi: 10.1016/j.exger.2021.111404.
Yair López and O. Axayacatl, “avocado analysis 2021 Production, Prices and Export,” 2021.
PERKENI, Pedoman Pengelolaan Dislipidemi di Indonesia 2019, 1st ed. PB Perkeni, 2019.
WHO, “Cardiovascular diseases (CVDs),” 2017.
C. P. B. Furlan, S. C. Valle, E. Östman, M. R. Maróstica, and J. Tovar, “Inclusion of Hass avocado-oil improves postprandial metabolic responses to a hypercaloric-hyperlipidic meal in overweight subjects,” J. Funct. Foods, vol. 38, pp. 349–354, 2017, doi: 10.1016/j.jff.2017.09.019.
C. X. Tan, G. H. Chong, H. Hamzah, and H. M. Ghazali, “Effect of virgin avocado oil on diet‐induced hypercholesterolemia in rats via 1H NMR‐based metabolomics approach,” Phyther. Res., vol. 32, no. 11, pp. 2264–2274, 2018, doi: 10.1002/ptr.6164.
C. X. Tan, G. H. Chong, H. Hamzah, and H. M. Ghazali, “Hypocholesterolaemic and hepatoprotective effects of virgin avocado oil in diet‐induced hypercholesterolaemia rats,” Int. J. Food Sci. & Technol., vol. 53, no. 12, pp. 2706–2713, 2018, doi: 10.1111/ijfs.13880.
C. I. García-Berumen et al., “Avocado oil alleviates non-alcoholic fatty liver disease by improving mitochondrial function, oxidative stress and inflammation in rats fed a high fat-High fructose diet.,” Front. Pharmacol., vol. 13, p. 1089130, 2022, doi: 10.3389/fphar.2022.1089130.
C. I. García-Berumen et al., “Avocado oil alleviates non-alcoholic fatty liver disease by improving mitochondrial function, oxidative stress and inflammation in rats fed a high fat–High fructose diet,” Front. Pharmacol., vol. 13, no. December, pp. 1–13, 2022, doi: 10.3389/fphar.2022.1089130.
O. A. R. Abozaid, S. A. H. Aziza, F. S. M. Moawed, and S. G. Kasseb, “Avocado Oil Attenuates Diethylnitrosamine Induced-Hepatic Carcinogenesis,” Benha Vet. Med. J., vol. 35, no. 2, pp. 344–353, 2018, doi: 10.21608/bvmj.2018.96425.
O. Carvajal-Zarrabal, C. Nolasco-Hipolito, M. G. Aguilar-Uscanga, G. M. Santiesteban, P. M. Hayward-Jones, and D. M. Barradas-Dermitz, “Effect of dietary intake of avocado oil and olive oil on biochemical markers of liver function in sucrose-fed rats,” Biomed Res. Int., 2014, doi: 10.1155/2014/595479.
O. Carvajal-Zarrabal, C. Nolasco-Hipolito, M. G. Aguilar-Uscanga, G. Melo Santiesteban, P. M. Hayward-Jones, and D. M. Barradas-Dermitz, “Effect of dietary intake of avocado oil and olive oil on biochemical markers of liver function in sucrose-fed rats.,” Biomed Res. Int., vol. 2014, p. 595479, 2014, doi: 10.1155/2014/595479.
O. Carvajal-Zarrabal, C. Nolasco-Hipolito, M. G. Aguilar-Uscanga, G. M. Santiesteban, P. M. Hayward-Jones, and D. M. Barradas-Dermitz, “Effect of Dietary Intake of Avocado Oil and Olive Oil on Biochemical Markers of Liver Function in Sucrose-Fed Rats,” Biomed Res. Int., vol. 2014, p. 595479, 2014, doi: 10.1155/2014/595479.
R. de Souza Abboud, V. Alves Pereira, C. A. Soares da Costa, G. Teles Boaventura, and M. Alves Chagas, “The Action Of Avocado Oil On The Lipidogram Of Wistar Rats Submitted To Prolonged Androgenic Stimulum.,” Nutr. Hosp., vol. 32, no. 2, pp. 696–701, Aug. 2015, doi: 10.3305/nh.2015.32.2.9009.
E. O. Gokkaya, S. Yesilot, M. Ozgocmen, R. Aslankoc, and C. Aydin Acar, “Protective effects of resveratrol and avocado oil against paracetamol-induced hepatotoxicity in rats,” Drug Chem. Toxicol., vol. 45, no. 5, pp. 2131–2139, 2022, doi: 10.1080/01480545.2021.1908716.
O. Carvajal-Zarrabal, C. Nolasco-Hipolito, M. G. Aguilar-Uscanga, G. Melo-Santiesteban, P. M. Hayward-Jones, and D. M. Barradas-Dermitz, “Avocado oil supplementation modifies cardiovascular risk profile markers in a rat model of sucrose-induced metabolic changes,” Dis. Markers, vol. 2014, 2014, doi: 10.1155/2014/386425.
O. Carvajal-Zarrabal, C. Nolasco-Hipolito, M. G. Aguilar-Uscanga, G. Melo-Santiesteban, P. M. Hayward-Jones, and D. M. Barradas-Dermitz, “Avocado oil supplementation modifies cardiovascular risk profile markers in a rat model of sucrose-induced metabolic changes.,” Dis. Markers, vol. 2014, p. 386425, 2014, doi: 10.1155/2014/386425.
V. A. P. Silva, G. T. Boaventura, R. de S. Abboud, J. A. Silva Ribas, and M. A. Chagas, “Consumption of avocado oil (Persea americana) improves the biochemical profile of rats submitted to long-term androgenic stimulation.,” Nutr. Hosp., vol. 37, no. 5, pp. 1033–1038, Oct. 2020, doi: 10.20960/nh.03155.
F. Gheshlaghi, M. R. Piri-Ardakani, G. R. Masoumi, M. Behjati, and P. Paydar, “Cardiovascular manifestations of anabolic steroids in association with demographic variables in body building athletes,” J. Res. Med. Sci., vol. 20, no. 2, pp. 165–168, 2015.
C. Sripratiwi, “Perubahan Berat dan Histologi Testis Tikus Putih Jantan (Rattus Norvegicus) Akibat Pemberian Fraksi Daun Jambu Biji Merah (Psidium Guajava L.),” Biomed. J. Indones. J. Biomedik Fak. Kedokt. Univ. Sriwij., vol. 5, no. 1, pp. 11–19, 2019, doi: 10.32539/bji.v5i1.7973.
E. Magriplis et al., “Trans fatty acid intake increases likelihood of dyslipidemia especially among individuals with higher saturated fat consumption,” Rev. Cardiovasc. Med., vol. 23, no. 4, 2022, doi: 10.31083/j.rcm2304130.
I. Yustisia, D. Tandiari, M. H. Cangara, F. Hamid, and N. A. Daud, “A high-fat, high-fructose diet induced hepatic steatosis, renal lesions, dyslipidemia, and hyperuricemia in non-obese rats,” Heliyon, vol. 8, no. 10, p. e10896, 2022, doi: 10.1016/j.heliyon.2022.e10896.
X. Cao et al., “The Effect of MUFA-Rich Food on Lipid Profile: A Meta-Analysis of Randomized and Controlled-Feeding Trials,” Foods, vol. 11, no. 13, 2022, doi: 10.3390/foods11131982.
K. P. Tritisari, “Asuhan Gizi Sirosis Hepatik,” in asuhan gizi klinik, 1st ed., I. dewa nyoman Supariasa and D. Handayani, Eds. jakarta: EGC, 2019, p. 500.
V. Alves et al., “Consumption of Green Tea ( Camellia sinensis ) Improves Lipid , Hepatic , and Hematological Profiles of Rats That Are Submitted to Long-Term Androgenic Stimulation,” Am. J. Sport. Sci., vol. 6, no. 4, pp. 162–168, 2018, doi: 10.11648/j.ajss.20180604.15.
S. Gupta et al., “Hepatocellular Neoplasms Arising in Association With Androgen Use,” Am. J. Surg. Pathol., vol. 40, no. 4, pp. 454–461, 2016, doi: 10.1097/PAS.0000000000000576.
F. A. Wani, A. Z. Albahrawy, and S. Rahiman, “Hypolipidemic Activity of Olive Oil (Olea europaea) against High Fat Diet-Induced Nonalcoholic Fatty Liver Disease (NAFLD) in Mice,” Open J. Pathol., vol. 05, no. 03, pp. 73–83, 2015, doi: 10.4236/ojpathology.2015.53011.
A. Raúl, G. Ruiz, J. Crespo, R. Maria, L. Martínez, and P. Iruzubieta, “Measurement and clinical usefulness of bilirubin in liver disease,” vol. 2, no. 3, pp. 352–361, 2021.
L. Žiberna, Z. Jenko-Pražnikar, and A. Petelin, “Serum bilirubin levels in overweight and obese individuals: The importance of anti-inflammatory and antioxidant responses,” Antioxidants, vol. 10, no. 9, 2021, doi: 10.3390/antiox10091352.
A. Ferramosca and V. Zara, “Modulation of hepatic steatosis by dietary fatty acids,” World J. Gastroenterol., vol. 20, no. 7, pp. 1746–1755, 2014, doi: 10.3748/wjg.v20.i7.1746.
F. M. Perla, M. Prelati, M. Lavorato, D. Visicchio, and C. Anania, “The Role of Lipid and Lipoprotein Metabolism in Non-Alcoholic Fatty Liver Disease,” 2017, doi: 10.3390/children4060046.
O. A. Abo-Zaid, F. S. Moawed, E. S. Ismail, and M. A. Farrag, “β-sitosterol attenuates high- fat diet-induced hepatic steatosis in rats by modulating lipid metabolism, inflammation and ER stress pathway,” BMC Pharmacol. Toxicol., vol. 24, no. 1, pp. 1–10, 2023, doi: 10.1186/s40360-023-00671-0.
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