EFFECT OF ETHANOL EXTRACT OF MORINGA LEAF (MORINGA OLEIFERA) ON THE NUMBER OF GERMS IN ANTISEPTIC PREPARATIONS

Authors

  • Asiska Permata Dewi Undergraduate Program in Pharmacy, Faculty of Pharmacy and Health Science University Abdurrab Pekanbaru Riau
  • Koni Putriani Undergraduate Program in Pharmacy, Faculty of Pharmacy and Health Science University Abdurrab Pekanbaru Riau
  • Vonny Kurnia Utama Undergraduate Program in Pharmacy, Faculty of Pharmacy and Health Science University Abdurrab Pekanbaru Riau
  • Nova Relida Physiotheraphy study program, Faculty of Pharmacy and Health Science University Abdurrab Pekanbaru Riau
  • Akmal Djamaan Department of Pharmacy, Faculty of Pharmacy University Andalas Padang, West Sumatera

Abstract

Moringa leaves (Moringa oleifera Lam) have benefits as antimicrobial, antibacterial, anti-inflammatory (anti-inflammatory), and viral infections. Moringa leaves contain secondary metabolites such as polyphenols consisting of non-flavonoids and flavonoids, phenols, tannins, saponins, alkaloids, and triterpenoids. This study aims to determine the effect of ethanol extract of Moringa leaves in hand sanitizer gel preparations on the number of germs  at concentrations of 2%, 4%, 6% and 8%. The research method for testing germ numbers is the total plate number method by looking at the number of bacterial colonies that die after using the antiseptic gel. The research results showed that the percentage of dead bacteria was at concentration 2%, 4%, 6%, and 8%, the positive control and the negative control were 16,10%; 38,6%; 44,44%; 62,55%; 86,45% and 14,11%. The higher the concentration of the extract in the gel preparation, the more the number of bacterial colonies that died.

References

Fahey JW. Moringaoleifera: A Review of the medical evidence for its nutritional. Therapeutic and prophylactic.Part 1. Trees for Life journal, 1:5. 2005

Savitri , E, Fakhrurrazi, Harris A. Uji Antibakteri Ekstrak Daun Kelor (Moringa oleifera L.) terhadap Pertumbuhan Bakteri Staphylococcus aureus. Jurnal Kedokteran Hewan . 2 (4): 373-379. 2018

Pandey A, Pandey RD, Tripathi P, Gupta PP, Haider J, Bhatt S, Singh AV. Moringaoleifera Lam. (Sahijan)- a plant with a plethora of diverse therapeutic benefits: an update retrospection. Medicinal and Aromatic Plants 1 (1) : 2-8. 2012

Kurniawan, Setyo. Obat Ajaib Sirih Merah dan Daun Kelor. Yogyakarta: Buku Biru. 2013

Pratiwi, S. T. Mikrobiologi Farmasi. Jakarta: Erlangga. 2008

Walidah, Isnaini, Bambang Supriyanta, dan Sujono. Daya Bunuh Hand Sanitizer Berbahan Aktif Alkohol 59% dalam Kemasan Setelah Penggunaan Berulang Terhadap Angka Lempeng Total (ALT). Journal Teknologi Laboratorium. 2014

Toripah SS, Abidjulu J, Wehantouw F. Aktivitas antioksidan dan kandungan ttal fenolik ekstrak daun kelor (Moringa oleifera Lam). Pharmacon 3 (4): 37-43. 2014

Untari, E. K., dan Robiyanto. Uji Fisikokimia dan Uji Iritasi Sabun Septik Kulit Daun Aloe vera (L.) Burm.f. Jurnal Jamu Indonesia. Volume 3 (2) : 55-61. 2018

Juwita, A. P., P.V. Yamlean, dan J. J. Edy. Formulasi Krim Ekstrak Etnaol Daun Lamun (Syringodium isoetifolium). Jurnal Ilmiah Farmasi UNSRAT. Volume 2 (02) : 8-12. 2013

Ardana, M., Aeyni, V., dan Arsyik I. Formulasi dan Optimasi Basis Gel HPMC (Hidroxy Propyl Methyl Cellulose) Dengan Berbagai Konsentrasi. J. Trop. Pharm. Chem. Vol 3 (2). 101-108. 2015

Manus, N., P. V. Y. Yamlean, dan N. S. Kojong. Formulasi Sediaan Gel Minyak Atsiri Daun Sereh (Cymbopogon citratus) Sebagi Antiseptik Tangan. Jurnal ilmiah farmasi. Vol 5(3): 87. 2016

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Published

2023-04-14