HUBUNGAN KEPATUHAN TERAPI ARV TERHADAP VIRAL LOAD DAN INFEKSI OPORTUNISTIK

Agus Alamsyah; Ikhtiyaruddin Ikhtiyaruddin; Christine Vita Gloria  Purba

doi:10.35328/kesmas.v13i2.2800

Authors

Agus Alamsyah Universitas Hang Tuah Pekanbaru , Indonesia
Ikhtiyaruddin Ikhtiyaruddin Universitas Hang Tuah Pekanbaru, Indonesia
Christine Vita Gloria Purba Universitas Hang Tuah Pekanbaru , Indonesia

DOI:

https://doi.org/10.35328/kesmas.v13i2.2800

Abstract

HIV/AIDS is one of the highest infectious diseases in the Limapuluh Community Health Center, with 305 cases. Of this number, 204 (66.9%) HIV patients were receiving ARV treatment and 102 (50%) patients were not adherent to ARV therapy. According to the results of the viral load examination, 86.3% of HIV patients had a suppressed viral load and 13.7% were not suppressed. A suppressed viral load is essential for maintaining their own health and reducing the risk of transmitting HIV to others. The aim of the research was to determine the relationship between adherence to ARV therapy and Viral Load and Opportunistic Infections. This type of observational analytical quantitative research with a cross-sectional study design. The population in this study were HIV patients who were undergoing ARV treatment at the Limapuluh Community Health Center, Pekanbaru City in 2024, totaling 204 patients. The sample size with an alpha of 5% was 84 respondents, with a simple random sampling technique. Collecting data on Therapy Adherence by interview using a questionnaire while collecting data on viral load and opportunistic infections using secondary data. Bivariate analysis uses the chi square test. The results of the study showed that there was no relationship between adherence to ARV therapy and Viral Load (p value 0.09) but the odds of Viral Load not complying with ARV therapy were 2.5 times higher than those complying with ARV therapy (POR = 2.5; 95% CI = 0 .9 -6.7). Adherence to ARV therapy is associated with opportunistic infections (P value = 0.013). The odds of opportunistic infections in those who do not adhere to ARV therapy are 3.8 times higher than those who adhere to ARV therapy. It is recommended that HIV-AIDS sufferers comply with ARV therapy so that they can reduce viral load levels and prevent opportunistic infectios

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